Archived page
National Cholesterol Education Program
Adult Treatment Panel III (ATP III) Guidelines Slide Set
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 11 | 12 | 13 | 14
SLIDE 1: ATP III Guidelines
Detection and Evaluation
SLIDE 2: Categories of Risk Factors
- Major, independent risk factors
- Life-habit risk factors
- Emerging risk factors
SLIDE 3: Life-Habit Risk Factors
- Obesity (BMI greater than or equal to30)
- Physical inactivity
- Atherogenic diet
SLIDE 4: Emerging Risk Factors
- Lipoprotein (a)
- Homocysteine
- Prothrombotic factors
- Proinflammatory factors
- Impaired fasting glucose
- Subclinical atherosclerosis
SLIDE 5: Risk Assessment
Count major risk factors
- For patients with multiple (2+) risk factors
- Perform 10-year risk assessment
- For patients with 0-1 risk factor
- 10 year risk assessment not required
- Most patients have 10-year risk <10%
SLIDE 6: Major Risk Factors (Exclusive of LDL Cholesterol) That Modify LDL Goals
- Cigarette smoking
- Hypertension (BP greater than or equal to140/90 mmHg or on antihypertensive medication)
- Low HDL cholesterol (<40 mg/dL)†
- Family history of premature CHD
- CHD in male first degree relative <55 years
- CHD in female first degree relative <65 years
- Age (men greater than or equal to45 years; women greater than or equal to55 years)
† HDL cholesterol greater than or equal to60 mg/dL counts as "negative" risk factor; its presence removes one risk factor from the total count.
SLIDE 7: Diabetes
In ATP III, diabetes is regarded as a CHD risk equivalent.
SLIDE 8: CHD Risk Equivalents
- Risk for major coronary events equal to that in established CHD
- 10-year risk for hard CHD >20%
Hard CHD=myocardial infarction + coronary death
SLIDE 9: Diabetes as a CHD Risk Equivalent
- 10-year risk for CHD
20% - High mortality with established CHD
- High mortality with acute MI
- High mortality post acute MI
SLIDE 10: CHD Risk Equivalents
- Other clinical forms of atherosclerotic disease (peripheral arterial disease, abdominal aortic aneurysm, and symptomatic carotid artery disease)
- Diabetes
- Multiple risk factors that confer a 10-year risk for CHD >20%
SLIDE 11: Three Categories of Risk that Modify LDL-Cholesterol
| Goals Risk Category | LDL Goal (mg/dL) |
|---|---|
| CHD and CHD risk equivalents | <100 |
| Multiple (2+) risk factors | <130 |
| Zero to one risk factor | <160 |
SLIDE 12: ATP III Lipid and Lipoprotein Classification
LDL Cholesterol (mg/dL)
- <100 Optimal
- 100-129 Near optimal/above optimal
- 130-159 Borderline high
- 160-189 High
- greater than or equal to190 Very high
SLIDE 13: ATP III Lipid and Lipoprotein Classification (continued)
HDL Cholesterol (mg/dL)
- <40 Low
- greater than or equal to60 High
SLIDE 14: ATP III Lipid and Lipoprotein Classification (continued)
Total Cholesterol (mg/dL)
- <200 Desirable
- 200-239 Borderline high
- greater than or equal to240 High Primary
Archived page, reproduced from a 2012 copy. It is reference material, not current guidance.