| | 1996-98 | Rate/100,000 | |
| Name | Deaths | Population | Crude | Age Adjusted | |
| DYER, TN-LAUDERDALE, TN -HSA# 248 | 730 | 206,252 | 353.9 | 335.8 |
| SCOTT, TN -HSA# 263 | 170 | 59,486 | 285.8 | 312.7 |
| CALLOWAY, KY-CARROLL, TN -HSA# 115 | 1,226 | 323,954 | 378.4 | 295.2 |
| PUTNAM, TN-OVERTON, TN -HSA# 215 | 1,174 | 363,198 | 323.2 | 293.8 |
| BELL, KY-CLAIBORNE, TN -HSA# 96 | 792 | 281,713 | 281.1 | 285.8 |
| LAWRENCE, TN-WAYNE, TN -HSA# 232 | 576 | 188,497 | 305.6 | 279.0 |
| GREENE, TN-COCKE, TN -HSA# 252 | 829 | 272,667 | 304.0 | 277.3 |
| SHELBY (MEMPHIS), TN-PANOLA, MS -HSA# 146 | 7,587 | 3,414,127 | 222.2 | 275.8 |
| SUMNER (HENDERSONVILLE), TN-WILSON, TN -HSA# 231 | 1,660 | 731,336 | 227.0 | 274.3 |
| HARDIN, TN-MC NAIRY, TN -HSA# 245 | 486 | 145,547 | 333.9 | 273.2 |
| MAURY, TN-GILES, TN -HSA# 208 | 1,037 | 399,654 | 259.5 | 265.2 |
| OBION, TN-WEAKLEY, TN -HSA# 181 | 705 | 217,388 | 324.3 | 263.7 |
| COFFEE, TN-FRANKLIN, TN -HSA# 239 | 872 | 305,231 | 285.7 | 261.8 |
| BEDFORD, TN -HSA# 260 | 284 | 102,545 | 277.0 | 259.9 |
| MADISON (JACKSON), TN-GIBSON, TN -HSA# 188 | 2,127 | 718,938 | 295.9 | 259.3 |
| RUTHERFORD (MURFREESBORO), TN-WARREN, TN -HSA# 211 | 1,370 | 685,352 | 199.9 | 258.8 |
| SULLIVAN (KINGSPORT), TN-WASHINGTON, VA -HSA# 151 | 3,071 | 1,049,398 | 292.6 | 257.0 |
| HAMILTON (CHATTANOOGA), TN-CATOOSA, GA -HSA# 141 | 3,600 | 1,372,233 | 262.3 | 255.0 |
| CUMBERLAND, TN-FENTRESS, TN -HSA# 223 | 625 | 208,774 | 299.4 | 249.0 |
| ANDERSON (OAK RIDGE), TN-ROANE, TN -HSA# 226 | 1,648 | 614,642 | 268.1 | 246.2 |
| HAMBLEN (MORRI), TN-JEFFERSON, TN -HSA# 217 | 890 | 365,870 | 243.3 | 242.2 |
| BRADLEY, TN-GILMER, GA -HSA# 173 | 970 | 397,555 | 244.0 | 242.0 |
| DAVIDSON (NASHVILLE-DAVIDSON), TN-DICKSON, TN -HSA# 148 | 5,085 | 2,428,583 | 209.4 | 239.4 |
| KNOX (KNOXVILLE), TN-BLOUNT, TN -HSA# 147 | 4,774 | 2,037,799 | 234.3 | 234.8 |
| WASHINGTON (JOHNSON CITY), TN-CARTER, TN -HSA# 169 | 1,310 | 514,411 | 254.7 | 224.5 |
| MONTGOMERY (CLARKSVILLE), TN-HOUSTON, TN -HSA# 234 | 593 | 429,561 | 138.0 | 205.8 |
| MADISON (HUNTSVILLE), AL-JACKSON, AL -HSA# 210 | 2,041 | 1,244,561 | 164.0 | 192.2 |
| WATAUGA, NC-ASHE, NC -HSA# 194 | 482 | 243,329 | 198.1 | 182.3 |
