| | 1996-98 | Rate/100,000 | |
| Name | Deaths | Population | Crude | Age Adjusted | |
| KERN (BAKERSFIELD), CA -HSA# 807 | 3,762 | 1,874,212 | 200.7 | 288.1 |
| SAN BERNARDINO, CA-RIVERSIDE (RIVERSIDE), CA -HSA# 768 | 18,934 | 9,160,880 | 206.7 | 266.2 |
| INYO, CA-MONO, CA -HSA# 816 | 246 | 85,799 | 286.7 | 259.8 |
| TULARE (VISALIA), CA -HSA# 789 | 1,921 | 1,051,326 | 182.7 | 236.4 |
| STANISLAUS (MODESTO), CA-MERCED, CA -HSA# 737 | 3,944 | 2,046,668 | 192.7 | 236.0 |
| LOS ANGELES (LOS ANGELES), CA-ORANGE, CA -HSA# 723 | 65,458 | 35,402,354 | 184.9 | 232.6 |
| WASHOE (RENO), NV-ORMSBY, NV -HSA# 701 | 2,718 | 1,420,878 | 191.3 | 225.2 |
| YUBA, CA-SUTTER (YUBA CITY), CA -HSA# 690 | 870 | 464,888 | 187.1 | 220.7 |
| SAN JOAQUIN (STOCKTON), CA-AMADOR, CA -HSA# 750 | 3,562 | 1,838,555 | 193.7 | 219.9 |
| FRESNO (FRESNO), CA-KINGS, CA -HSA# 718 | 4,836 | 2,932,224 | 164.9 | 211.1 |
| SACRAMENTO (SACRAMENTO), CA-PLACER, CA -HSA# 709 | 8,779 | 5,041,638 | 174.1 | 207.0 |
| SOLANO (VALLEJO), CA-NAPA, CA -HSA# 746 | 2,942 | 1,633,106 | 180.1 | 203.1 |
| MENDOCINO, CA -HSA# 811 | 527 | 249,952 | 210.8 | 203.0 |
| COOS, OR-DEL NORTE, CA -HSA# 738 | 850 | 331,547 | 256.4 | 201.0 |
| SAN DIEGO (SAN DIEGO), CA-IMPERIAL, CA -HSA# 774 | 14,550 | 8,588,679 | 169.4 | 200.6 |
| HUMBOLDT, CA -HSA# 800 | 689 | 367,223 | 187.6 | 198.2 |
| ALAMEDA (OAKLAND), CA-CONTRA COSTA, CA -HSA# 766 | 11,373 | 6,819,733 | 166.8 | 195.7 |
| SHASTA (REDDING), CA-MODOC, CA -HSA# 710 | 1,157 | 556,256 | 208.0 | 195.4 |
| VENTURA (OXNARD), CA -HSA# 790 | 3,107 | 2,165,219 | 143.5 | 182.6 |
| SANTA BARBARA (SANTA BARBARA), CA-SAN LUIS OBISPO, CA -HSA# 781 | 3,561 | 1,852,522 | 192.2 | 182.4 |
| SAN FRANCISCO (SAN FRANCISCO), CA-SAN MATEO, CA -HSA# 757 | 8,597 | 4,304,111 | 199.7 | 181.5 |
| JACKSON (MEDFORD), OR-JOSEPHINE, OR -HSA# 752 | 1,978 | 863,833 | 229.0 | 181.2 |
| PLUMAS, CA-LASSEN, CA -HSA# 780 | 254 | 159,188 | 159.6 | 179.4 |
| BUTTE (CHICO), CA-TEHAMA, CA -HSA# 697 | 1,728 | 819,720 | 210.8 | 177.9 |
| SONOMA (SANTA ROSA), CA-MARIN, CA -HSA# 764 | 3,650 | 1,982,867 | 184.1 | 177.1 |
| SANTA CRUZ (SANTA CRUZ), CA -HSA# 802 | 1,129 | 717,695 | 157.3 | 175.9 |
| SANTA CLARA (SAN JOSE), CA-MONTEREY, CA -HSA# 751 | 8,185 | 6,069,656 | 134.9 | 175.8 |
| NEVADA, CA-SIERRA, CA -HSA# 753 | 589 | 279,815 | 210.5 | 169.9 |
