| | 1996-98 | Rate/100,000 | |
| Name | Deaths | Population | Crude | Age Adjusted | |
| WILLIAMS, OH-DEFIANCE, OH -HSA# 356 | 10 | 383,869 | 2.6 | 2.7 | UNSTABLE |
| ALLEN (LIMA), OH-MERCER, OH -HSA# 292 | 24 | 878,551 | 2.7 | 2.6 |
| CABELL (HUNTINGTON), WV-BOYD, KY -HSA# 46 | 30 | 1,094,505 | 2.7 | 2.6 |
| CLINTON, OH-HIGHLAND, OH -HSA# 372 | 6 | 237,933 | 2.5 | 2.5 | UNSTABLE |
| HAMILTON (CINCINNATI), OH-BUTLER, OH -HSA# 270 | 98 | 4,746,174 | 2.1 | 2.1 |
| MONTGOMERY (DAYTON), OH-GREENE, OH -HSA# 295 | 53 | 2,448,465 | 2.2 | 2.1 |
| MUSKINGUM, OH-GUERNSEY, OH -HSA# 377 | 15 | 670,893 | 2.2 | 2.1 | UNSTABLE |
| WOOD (PARKERSBURG), WV-WASHINGTON, OH -HSA# 34 | 16 | 674,982 | 2.4 | 2.1 | UNSTABLE |
| LUCAS (TOLEDO), OH-MONROE, MI -HSA# 276 | 49 | 2,378,683 | 2.1 | 2.1 |
| LOGAN, OH -HSA# 398 | 3 | 137,593 | 2.2 | 2.1 | UNSTABLE |
| JEFFERSON (STEUBENVILLE), OH-HARRISON, OH -HSA# 360 | 6 | 275,931 | 2.2 | 2.0 | UNSTABLE |
| MAHONING (YOUNG), OH-MERCER, PA -HSA# 345 | 40 | 1,819,913 | 2.2 | 2.0 |
| CUYAHOGA (CLEVELAND), OH-LAKE, OH -HSA# 288 | 119 | 5,418,297 | 2.2 | 2.0 |
| RICHLAND (MANSFIELD), OH-ASHLAND, OH -HSA# 369 | 11 | 542,942 | 2.0 | 1.9 | UNSTABLE |
| FRANKLIN (COLUMBUS), OH-DELAWARE, OH -HSA# 281 | 59 | 3,695,575 | 1.6 | 1.8 |
| OHIO (WHEELING), WV-BELMONT, OH -HSA# 24 | 13 | 599,745 | 2.2 | 1.8 | UNSTABLE |
| COLUMBIANA, OH-HANCOCK (WEIRTON), WV -HSA# 380 | 9 | 515,785 | 1.7 | 1.6 | UNSTABLE |
| CLARK (SPRINGFIELD), OH-CHAMPAIGN, OH -HSA# 346 | 9 | 552,274 | 1.6 | 1.5 | UNSTABLE |
| LORAIN (LORAIN), OH-ERIE, OH -HSA# 366 | 21 | 1,446,980 | 1.5 | 1.5 |
| STARK (CANTON), OH-TUSCARAWAS, OH -HSA# 347 | 27 | 1,912,121 | 1.4 | 1.3 |
| HANCOCK, OH-SENECA, OH -HSA# 386 | 5 | 386,381 | 1.3 | 1.3 | UNSTABLE |
| FAIRFIELD (LANCASTER), OH-ATHENS, OH -HSA# 368 | 8 | 671,356 | 1.2 | 1.2 | UNSTABLE |
| SUMMIT (AKRON), OH-MEDINA, OH -HSA# 352 | 31 | 2,484,238 | 1.2 | 1.2 |
| SCIOTO, OH-ROSS, OH -HSA# 337 | 7 | 590,297 | 1.2 | 1.1 | UNSTABLE |
| MARION, OH-CRAWFORD, OH -HSA# 354 | 7 | 621,220 | 1.1 | 1.1 | UNSTABLE |
| GALLIA, OH-MASON, WV -HSA# 283 | 2 | 345,881 | 0.6 | 0.5 | UNSTABLE |
| LICKING (NEWARK), OH-KNOX, OH -HSA# 388 | 3 | 552,457 | 0.5 | 0.5 | UNSTABLE |
| MIAMI (PIQUA), OH-SHELBY, OH -HSA# 376 | 2 | 434,628 | 0.5 | 0.5 | UNSTABLE |
