| | 1995-97 | Rate/100,000 |
| Name | Deaths | Population | Crude | Age Adjusted |
| LOGAN, OH | 5 | 142,143 | 3.5 | 3.2 |
| WOOD (PARKERSBURG), WV - WASHINGTON, OH | 17 | 698,875 | 2.4 | 1.9 |
| MONTGOMERY (DAYTON), OH - GREENE, OH | 49 | 2,501,818 | 2.0 | 1.9 |
| MUSKINGUM, OH - GUERNSEY, OH | 17 | 691,602 | 2.5 | 1.9 |
| CABELL (HUNTINGTON), WV - BOYD, KY | 25 | 1,137,781 | 2.2 | 1.9 |
| CLINTON, OH - HIGHLAND, OH | 5 | 244,565 | 2.0 | 1.8 |
| HAMILTON (CINCINNATI), OH - BUTLER, OH | 95 | 4,921,053 | 1.9 | 1.7 |
| LUCAS (TOLEDO), OH - MONROE, MI | 42 | 2,472,921 | 1.7 | 1.6 |
| CLARK (SPRINGFIELD), OH - CHAMPAIGN, OH | 12 | 576,117 | 2.1 | 1.6 |
| HANCOCK, OH - SENECA, OH | 8 | 401,310 | 2.0 | 1.6 |
| CUYAHOGA (CLEVELAND), OH - LAKE, OH | 109 | 5,652,418 | 1.9 | 1.5 |
| ALLEN (LIMA), OH - MERCER, OH | 15 | 915,173 | 1.6 | 1.5 |
| FRANKLIN (COLUMBUS), OH - DELAWARE, OH | 63 | 3,824,497 | 1.6 | 1.5 |
| MAHONING (YOUNG), OH - MERCER, PA | 38 | 1,891,528 | 2.0 | 1.5 |
| WILLIAMS, OH - DEFIANCE, OH | 9 | 398,492 | 2.3 | 1.5 |
| LORAIN (LORAIN), OH - ERIE, OH | 19 | 1,507,592 | 1.3 | 1.3 |
| OHIO (WHEELING), WV - BELMONT, OH | 11 | 616,615 | 1.8 | 1.2 |
| COLUMBIANA, OH - HANCOCK (WEIRTON), WV | 8 | 534,755 | 1.5 | 1.2 |
| FAIRFIELD (LANCASTER), OH - ATHENS, OH | 8 | 688,096 | 1.2 | 1.1 |
| GALLIA, OH - MASON, WV | 5 | 356,862 | 1.4 | 1.1 |
| SCIOTO, OH - ROSS, OH | 8 | 611,419 | 1.3 | 1.1 |
| STARK (CANTON), OH - TUSCARAWAS, OH | 26 | 1,986,442 | 1.3 | 1.1 |
| RICHLAND (MANSFIELD), OH - ASHLAND, OH | 6 | 560,153 | 1.1 | 1.0 |
| JEFFERSON (STEUBENVILLE), OH - HARRISON, OH | 4 | 288,399 | 1.4 | 0.8 |
| MARION, OH - CRAWFORD, OH | 6 | 633,591 | 0.9 | 0.8 |
| SUMMIT (AKRON), OH - MEDINA, OH | 22 | 2,555,189 | 0.9 | 0.8 |
| MIAMI (PIQUA), OH - SHELBY, OH | 4 | 450,090 | 0.9 | 0.7 |
| LICKING (NEWARK), OH - KNOX, OH | 6 | 591,710 | 1.0 | 0.7 |
