| | 1995-97 | Rate/100,000 |
| Name | Deaths | Population | Crude | Age Adjusted |
| POWESHIEK, IA | 4 | 58,652 | 6.8 | 5.5 |
| LUCAS, IA - WAYNE, IA | 3 | 49,201 | 6.1 | 5.4 |
| PAGE, IA - FREMONT, IA | 6 | 99,419 | 6.0 | 4.7 |
| SCOTT (DAVENPORT), IA - MUSCATINE, IA | 20 | 619,884 | 3.2 | 3.2 |
| CERRO GORDO, IA - KOSSUTH, IA | 13 | 332,702 | 3.9 | 2.8 |
| POTTAWATTAMIE (COUNCIL BLUFFS), IA - SHELBY, IA | 16 | 462,586 | 3.5 | 2.6 |
| MARTIN, MN - EMMET, IA | 3 | 103,341 | 2.9 | 2.4 |
| WOODBURY (SIOUX CITY), IA - BUENA VISTA, IA | 20 | 659,294 | 3.0 | 2.4 |
| WAPELLO, IA - MAHASKA, IA | 9 | 315,262 | 2.9 | 2.3 |
| LA CROSSE (LA CROSSE), WI - MONROE, WI | 22 | 707,968 | 3.1 | 2.1 |
| OLMSTED (ROCHESTER), MN - WINONA, MN | 24 | 929,838 | 2.6 | 2.1 |
| BLACK HAWK (WATERLOO), IA - FAYETTE, IA | 18 | 673,366 | 2.7 | 2.0 |
| SIOUX, IA | 2 | 96,903 | 2.1 | 2.0 |
| MINNEHAHA (SIOUX FALLS), SD - LAKE, SD | 15 | 740,879 | 2.0 | 1.9 |
| LINN (CEDAR RAPIDS), IA - JOHNSON, IA | 24 | 1,224,987 | 2.0 | 1.8 |
| CLAY, IA - DICKINSON, IA | 3 | 134,255 | 2.2 | 1.7 |
| LEE, IA - HANCOCK, IL | 6 | 209,566 | 2.9 | 1.5 |
| CRAWFORD, WI - CLAYTON, IA | 3 | 166,347 | 1.8 | 1.4 |
| DUBUQUE (DUBUQUE), IA - STEPHENSON, IL | 10 | 558,501 | 1.8 | 1.4 |
| DES MOINES, IA - HENRY, IA | 4 | 220,438 | 1.8 | 1.4 |
| CLINTON, IA - WHITESIDE, IL | 8 | 420,363 | 1.9 | 1.4 |
| WINNESHIEK, IA | 1 | 64,707 | 1.5 | 1.3 |
| CARROLL, IA - CALHOUN, IA | 3 | 139,712 | 2.1 | 1.3 |
| MARSHALL, IA - TAMA, IA | 3 | 176,292 | 1.7 | 1.3 |
| CRAWFORD, IA | 1 | 51,195 | 2.0 | 1.2 |
| GREENE, IA - GUTHRIE, IA | 2 | 66,564 | 3.0 | 1.1 |
| STORY, IA - HAMILTON, IA | 7 | 463,619 | 1.5 | 1.1 |
| FLOYD, IA - CHICKASAW, IA | 1 | 92,942 | 1.1 | 1.0 |
| POLK (DES MOINES), IA - MARION, IA | 21 | 1,721,056 | 1.2 | 1.0 |
| OBRIEN, IA - OSCEOLA, IA | 2 | 68,891 | 2.9 | 1.0 |
| MONTGOMERY, IA - ADAMS, IA | 1 | 50,729 | 2.0 | 0.9 |
| WEBSTER, IA - HUMBOLDT, IA | 3 | 180,941 | 1.7 | 0.8 |
| MITCHELL, IA | 0 | 34,394 | 0.0 | 0.0 |
| APPANOOSE, IA - DAVIS, IA | 0 | 68,420 | 0.0 | 0.0 |
